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Antigenic Specificity | WDR34 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Critical for ciliary functions, essential to normal development and survival, most probably as a previously unrecognized component of the mammalian dynein-motor-based intraflagellar transport (IFT) machinery. Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Inhibits the MAP3K7-induced NF-kappa-B activation pathway. Inhibits MAP3K7 phosphorylation at 'Thr-184' and 'Thr-187' upon Il-1 beta stimulation. |
Immunogen | Immunogen: Recombinant human WD repeat-containing protein 34 protein |
Other Names | [WD repeat-containing protein 34; WDR34] |
Gene, Accession # | [WDR34], Gene ID: 89891, NCBI: NP_443076.2, UniProt: Q96EX3 |
Catalog # | MBS7000084 |
Price | $160, $235 |
Order / More Info | WDR34 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |