Edit |   |
Antigenic Specificity | Collagen III |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Collagen alpha-1(III) chain(COL3A1) detection. Tested with WB in Human. Background: COL3A1, also called EDS4A or Collagen alpha-1(III), is a protein that in humans is encoded by the COL3A1 gene, it is mapped to 2q32.2. COL3A1 chain is a fibrillar-forming collagen comprising 3 alpha-1(III) chains and is expressed in early embryos and throughout embryogenesis. In adult, COL3A1 is a major component of the extracellular matrix in a variety of internal organs and skin. COL3A1 is also a fibrous scleroprotein in bone, cartilage, dentin, tendon, bone marrow stroma and other connective tissue. It is involved in regulation of cortical development, and it Is the major ligand of GPR56 in the developing br |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Collagen III(1200-1221aa VGAAAIAGIGGEKAGGFAPYYG), different from the related mouse sequence by four amino acids, and from the related rat sequence by five amino acids. Ig Type: Rabbit IgG |
Other Names | [Collagen alpha-1(III) chain; CO3A1_HUMAN; COL 3A1; COL3A1; Collagen alpha 1(III) chain; Collagen alpha-1(III) chain; Collagen III alpha 1 chain precursor; Collagen III alpha 1 polypeptide; Collagen type III alpha 1 (Ehlers Danlos syndrome type IV autosomal dominant); Collagen type III alpha 1; Collagen type III alpha; EDS4A; Ehlers Danlos syndrome type IV, autosomal dominant; Fetal collagen; Type III collagen; collagen, type III, alpha 1], [COL3A1; COL3A1; EDS4A] |
Gene, Accession # | Gene ID: 1281, NCBI: NP_000081.1, UniProt: P02461 |
Catalog # | MBS177812 |
Price | $280 |
Order / More Info | Collagen III Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Janeczko RA, Ramirez F (Oct 1989). Nucleotide and amino acid sequences of the entire human alpha 1 (III) collagen. Nucleic Acids Res 17 (16): 6742. 2. Superti-Furga A, Gugler E, Gitzelmann R, Steinmann B (Jun 1988). Ehlers-Danlos syndrome type IV: a multi-exon deletion in one of the two COL3A1 alleles affecting structure, stability, and processing of type III procollagen. J Biol Chem 263 (13): 6226-32. |