PIST (C-term), 361-390 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPIST (C-term), 361-390
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis PIST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 361-390 amino acids from the C-terminal region of human PIST. PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner. PIST, a PDZ domain-containing Golgi protein, was discovered in a yeast two-hybrid system as a binding partner to Beclin-1, a Bcl-2-interacting protein homologous to the yeast autophagy gene apg6. Experiments with mutant PIST proteins lacking the PDZ domain showed that PIST interaction with Beclin-1 through its coiled-coil domain can modulate Beclin-1 activity and suggest that PIST interactions with other proteins through its PDZ domain may regulate the acti
Immunogenn/a
Other Names[Golgi-associated PDZ and coiled-coil motif-containing protein; CFTR-associated ligand; Fused in glioblastoma; PDZ protein interacting specifically with TC10; PIST; GOPC; CAL; FIG]
Gene, Accession #[GOPC], Gene ID: 57120, NCBI: NP_001017408.1, UniProt: Q9HD26
Catalog #MBS9206639
Price$165, $370
Order / More InfoPIST (C-term), 361-390 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLi,X., Protein Sci. 15 (9), 2149-2158 (2006) Ito,H., Biochem. J. 397 (3), 389-398 (2006) Wente,W., J. Biol. Chem. 280 (37), 32419-32425 (2005)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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