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Antigenic Specificity | MER |
Clone | [7E5G1] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: MER (c-mer proto-oncogene tyrosine kinase) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. MER has been identified as a tyrosine kinase potentially involved in the development of glioblastomas. It is expressed at highest levels in ovary, prostate, lung and kidney. Gas6, a growth arrest specific gene, and the related anticoagulation factor Protein S have been identified as ligands for the UFO family of receptors. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessiv |
Immunogen | Immunogen: Purified recombinant fragment of MER expressed in E Coli. |
Other Names | [MER; RP38; c-mer; MGC133349; MERTK], [MER; RP38; c-mer; MGC133349; MERTK] |
Gene, Accession # | [MER], Gene ID: 10461 |
Catalog # | MBS475762 |
Price | $335 |
Order / More Info | MER Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |