NCSTN Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NCSTN |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous level of total NCSTN protein. Nicastrin is a transmembrane glycoprotein serving as an essential component of the g-secretase complex (1,2). Nicastrin is physically associated with presenilin and plays an important role in the stabilization and correct localization of presenilin to the membrane-bound g-secretase complex (3). Nicastrin also serves as a docking site for g-secretase substrates such as APP and Notch, directly binding to them and properly presenting them to g-secretase to ensure the correct cleavage process (2,4). |
| Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human NCSTN. |
| Other Names | [NCSTN; APH2; KIAA0253] |
| Gene, Accession # | [NCSTN], Gene ID: 23385, NCBI: NP_001277113.1, UniProt: Q92542 |
| Catalog # | MBS9404831 |
| Price | $255 |
| Order / More Info | NCSTN Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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