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Antigenic Specificity | BBC3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 2.5mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. |
Immunogen | Immunogen: Synthetic peptide of human BBC3 Calculated Molecular Weight: 21kDa |
Other Names | [JFY1; PUMA; JFY-1] |
Gene, Accession # | [BBC3], Gene ID: 27113, NCBI: NP_001120714.1 |
Catalog # | MBS2520788 |
Price | $110, $150, $225 |
Order / More Info | BBC3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |