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Antigenic Specificity | CCR8 (EL) (HIV and chemokine receptor) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and murine CCR8 were cloned and designated TER1, CKR-L1, and ChemR11-4. The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains5. CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines. |
Immunogen | Immunogen: Antibody raised against a synthetic peptide corresponding to amino acids 183 to 201 of the human CCR8. Peptide sequence is located in the second extracellular loop. |
Other Names | [C-C chemokine receptor type 8; Chemokine receptor-like 1; CDw198; GPR-Cy6], [CCR8; CCR8; CY6; TER1; CCR-8; CKRL1; CDw198; CMKBR8; GPRCY6; CMKBRL2; CC-CKR-8; CKRL1; CMKBR8; CMKBRL2; C-C CKR-8; CC-CKR-8; CCR-8; CKR-L1; GPRCY6] |
Gene, Accession # | [CCR8], Gene ID: 1237, NCBI: NP_005192.1, UniProt: P51685 |
Catalog # | MBS396066 |
Price | $510 |
Order / More Info | CCR8 (EL) (HIV and chemokine receptor) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |