Edit |   |
---|---|
Antigenic Specificity | FCGR2B (C-term), 250-279 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.38 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This FCGR2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-279 amino acids from the C-terminal region of human FCGR2B. The protein encoded by this gene is a low affinityreceptor for the Fc region of immunoglobulin gamma complexes. Theencoded protein is involved in the phagocytosis of immune complexesand in the regulation of antibody production by B-cells. Variationsin this gene may increase susceptibilty to systemic lupuserythematosus (SLE). Several transcript variants encoding differentisoforms have been found for this gene. |
Immunogen | n/a |
Other Names | [Low affinity immunoglobulin gamma Fc region receptor II-b; IgG Fc receptor II-b; CDw32; Fc-gamma RII-b; Fc-gamma-RIIb; FcRII-b; CD32; FCGR2B; CD32; FCG2; IGFR2] |
Gene, Accession # | [FCGR2B], Gene ID: 2213, NCBI: NP_001002273.1, UniProt: P31994 |
Catalog # | MBS9201898 |
Price | $165, $370 |
Order / More Info | FCGR2B (C-term), 250-279 Antibody from MYBIOSOURCE INC. |
Product Specific References | Prokopec, K.E., et al. Clin. Immunol. 137(3):322-329(2010) Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010) Zhang, C.Y., et al. J. Biol. Chem. 285(44):34250-34258(2010) Niederer, H.A., et al. Hum. Mol. Genet. 19(16):3282-3294(2010) Guilabert, A., et al. J. Am. Acad. Dermatol. 63(1):161-163(2010) |