mTOR Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitymTOR
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionRecognizes human and mouse mTOR. Detects a band of ~289kDa by Western blot. Mammalian target of rapamycin (mTOR) is an atypical serine-threonine protein kinase and member of the phosphatidylinositol 3-kinase (PI3K) signaling pathway. TORC1 (mTOR, G beta L/mLST8 and Raptor) and TORC2 (mTOR, G beta L/mLST8, SIN1, and Rictor) complexes control protein synthesis through the direct or indirect phosphorylation of downstream targets such as S6 Kinase and 4EBP1, key regulators of mRNA recruitment to ribosomes. Through its involvement in several key signaling pathways and its critical role in transcription and translation, mTOR mediates cell proliferation, differentiation, and survival. Studies identified the TORC2 complex as the missing kinase acti
ImmunogenImmunogen: Synthetic peptide corresponding to a portion of human mTOR.
Other Names[FRAP; FK506 binding protein 12-rapamycin associated protein], [MTOR; MTOR; SKS; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; mTOR]
Gene, Accession #[mTOR], Gene ID: 2475, NCBI: P42345.1, UniProt: P42345
Catalog #MBS565350
Price$385
Order / More InfomTOR Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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