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Antigenic Specificity | SIRT1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for NAD-dependent protein deacetylase sirtuin-1(SIRT1) detection. Tested with WB in Human. Background: Sirtuin 1, also known as SIR2L1 or SIRT1, is a protein that in humans is encoded by the SIRT1 gene. It is mapped to 10q21.3. Sirtuin 1 is a member of the sirtuin family of proteins, homologs of the Sir2 gene in S. cerevisiae. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. Sirtuin 1 is downregulated in cells that have high insulin resistance and inducing its expression increases insulin sensitivity, suggesting the molecule is associated with improving insulin sensitivity. Furthermore, Sirtuin 1 was shown to de-acetylate and affect the activi |
Immunogen | Immunogen: E.coli-derived human SIRT1 recombinant protein (Position: R112-K311). Human SIRT1 shares 90% amino acid (aa) sequence identity with mouse SIRT1. |
Other Names | [75SirT1; BA57G10.4; hSIR2; hSIRT1; HST2, S. cerevisiae, homolog of; NAD dependent deacetylase SIRT1; NAD dependent deacetylase sirtuin 1; NAD dependent protein deacetylase sirtuin 1; OTTHUMP00000198111; OTTHUMP00000198112; Regulatory protein SIR2 homolog 1; SIR1_HUMAN; SIR2 like 1; SIR2 like protein 1; SIR2, S.cerevisiae, homolog-like 1; SIR2-like protein 1; SIR2ALPHA; SIR2alpha protein; SIR2L1; SIRT 1; Sirt1; SIRT1 Sir2 like proteins (siruitins) type 1; SIRT1: sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae); SirtT1 75 kDa fragment; sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae); Sirtuin 1; sirtuin; Sirtuin type 1; sirtuin 1], [SIRT1; SIRT1; SIR2L1; SIR2L1; hSIRT1; hSIR2; 75SirT1] |
Gene, Accession # | [SIRT1], Gene ID: 23411, NCBI: NP_001135970.1, UniProt: Q96EB6 |
Catalog # | MBS177519 |
Price | $280 |
Order / More Info | SIRT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |