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Antigenic Specificity | VPS39 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Regulator of TGF-beta/activin signaling, inhibiting SMAD3-and activating SMAD2-dependent transcription. Acts by interfering with SMAD3/SMAD4 complex formation, this would lead to inhibition of SMAD3-dependent transcription and relieve SMAD3 inhibition of SMAD2-dependent promoters, thus increasing SMAD2-dependent transcription. Does not affect TGF-beta-induced SMAD2 or SMAD3 phosphorylation, nor SMAD2/SMAD4 complex formation. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 606-875 of human VPS39 (NP 056104.2). |
Other Names | [TLP; VAM6; hVam6p] |
Gene, Accession # | [VPS39], NCBI: AAQ05978, UniProt: Q96JC1 |
Catalog # | MBS8548814 |
Price | $280 |
Order / More Info | VPS39 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |