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Antigenic Specificity | CYP7A1-C |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous levels of CYP7A1(C-term) and does not cross-react with related proteins. UniPort Summary Function: Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis. Entrez Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This react |
Immunogen | Immunogen: Purified recombinant human CYP7A1(C-term) protein fragments expressed in E Coli. Cellular Localization: Endoplasmic reticulum membrane; Peripheral membrane protein |
Other Names | [CP7A; CYP7; CYPVII; MGC126826; MGC138389], [CP7A; CYP7; CYPVII] |
Gene, Accession # | [CYP7A1-C], Gene ID: 1581, NCBI: NP_000771.2, UniProt: P22680 |
Catalog # | MBS857808 |
Price | $300 |
Order / More Info | CYP7A1-C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |