Edit |   |
---|---|
Antigenic Specificity | FAP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This FAP antibody is generated from rabbits immunized with the protein of human FAP. The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. |
Immunogen | n/a |
Other Names | [Prolyl endopeptidase FAP; 170 kDa melanoma membrane-bound gelatinase; Dipeptidyl peptidase FAP; Fibroblast activation protein alpha; FAPalpha; Serine integral membrane protease; SIMP; Surface-expressed protease; Seprase; Antiplasmin-cleaving enzyme FAP; soluble form; APCE; 3421-; FAP HGNC:3590)] |
Gene, Accession # | [FAP], Gene ID: 2191, NCBI: NP_004451.2, UniProt: Q12884 |
Catalog # | MBS9206104 |
Price | $165, $370 |
Order / More Info | FAP Antibody from MYBIOSOURCE INC. |
Product Specific References | Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Ospelt, C., et al. Arthritis Rheum. 62(5):1224-1235(2010) Stremenova, J., et al. Int. J. Oncol. 36(2):351-358(2010) Chen, H., et al. Exp. Mol. Pathol. 87(3):189-194(2009) Dohi, O., et al. Histopathology 55(4):432-440(2009) |