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Antigenic Specificity | DUSP12 (Center), 162-191 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This DUSP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-191 amino acids from the Central region of human DUSP12. The protein encoded by this gene is a member of the dualspecificity protein phosphatase subfamily. These phosphatasesinactivate their target kinases by dephosphorylating both thephosphoserine/threonine and phosphotyrosine residues. Theynegatively regulate members of the mitogen-activated protein (MAP)kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associatedwith cellular proliferation and differentiation. Different membersof the family of dual specificity phosphatases show distinctsubstrate specificities for various MAP kinases, different |
Immunogen | n/a |
Other Names | [Dual specificity protein phosphatase 12; Dual specificity tyrosine phosphatase YVH1; DUSP12] |
Gene, Accession # | [DUSP12], Gene ID: 11266, NCBI: NP_009171.1, UniProt: Q9UNI6 |
Catalog # | MBS9210844 |
Price | $165, $370 |
Order / More Info | DUSP12 (Center), 162-191 Antibody from MYBIOSOURCE INC. |
Product Specific References | Biernacki, M.A., et al. Cancer Res. 70(3):906-915(2010) Bonham, C.A., et al. J. Biol. Chem. 284(34):22853-22864(2009) Sharda, P.R., et al. Biochem. J. 418(2):391-401(2009) Gao, F., et al. Zhonghua Yi Xue Za Zhi 88(32):2250-2253(2008) Hasstedt, S.J., et al. Ann. Hum. Genet. 72 (PT 2), 163-169 (2008) : |