CACYBP Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCACYBP
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat.
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionRabbit IgG polyclonal antibody for Calcyclin-binding protein (CACYBP) detection. Background: Calcyclin-binding protein is a protein that in humans is encoded by the CACYBP gene. And this gene is mapped to 1q24-q25. The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. In addition, it probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human CACYBP (7-47aa QKDLEEVKVLLEKATRKRVRDALTAEKSKIETEIKNKMQQK), different from the related mouse sequence by five amino acids, and from the related rat sequence by six amino acids.
Other Names[CACYBP; Calcyclin-binding protein; GIG5; hCacyBP; PNAS107; S100A6-binding protein; S100A6BP; S100A6BP; SIP; SIAH Interacting Protein; Siah-interacting protein; Q9HB71 ; Calcyclin-binding protein; calcyclin binding protein], [CACYBP; CACYBP; SIP; GIG5; PNAS-107; S100A6BP; S100A6BP; SIP; CacyBP; hCacyBP]
Gene, Accession #[CACYBP], Gene ID: 27101, NCBI: NP_001007215.1, UniProt: Q9HB71
Catalog #MBS178406
Price$315
Order / More InfoCACYBP Antibody from MYBIOSOURCE INC.
Product Specific References1. Matsuzawa, S., Reed, J. C. Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses.Molec. Cell 7: 915-926, 2001.2. Sun S, Ning X, Liu J, et al. (2007). Overexpressed CacyBP/SIP leads to the suppression of growth in renal cell carcinoma.. Biochem. Biophys. Res. Commun. 356 (4): 864-71.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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