TARDBP Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | TARDBP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.06 mL, 0.12 mL, 0.2 mL |
| Concentration | 1mg/mL |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorscence (IF), Immunoprecipitation (IP), RIP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TDP43 (TAR DNA-binding protein 43) is involved in transcriptional regulation and exon splicing (1, 2). While normal TDP43 is a nuclear protein, pathological TDP43 is a component of insoluble aggregates in patients with frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). In these disorders, TDP43 is abnormally ubiquitinated, phosphorylated and cleaved to generate carboxy-terminal fragments that are sequestered as insoluble aggregates in neuronal nuclei, perikarya, and neurites (3, 4). Additionally, TDP43 inhibits the expression of the HIV-1 gene and regulates CFTR gene splicing (1, 5). |
| Immunogen | Immunogen: Recombinant protein of human TARDBP Observed Molecular Weight: 43kDa |
| Other Names | [TARDBP; ALS10; TDP-43; Tdp43; TDP 43] |
| Gene, Accession # | [TARDBP], NCBI: CAG38565.1, UniProt: Q13148 |
| Catalog # | MBS2527670 |
| Price | $150, $225, $360 |
| Order / More Info | TARDBP Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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