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Antigenic Specificity | Rabbit Chk1 (Ab-317) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence/Immunocytochemistry (IF/ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Chk1 (Ser317) Ab detects endogenous levels of Chk1 only when phosphorylated at Serine 317. DNA damage induced protein phosphorylation; regulation of mitotic centrosome separation; regulation of S phase; peptidyl-threonine phosphorylation; DNA repair; chromatinmediated maintenance of transcription; negative regulation of mitosis; |
Immunogen | Immunogen: A synthesized peptide derived from human Chk1 around the phosphorylation site of Ser317. Subcellular Location: Cytoskeleton;Nucleus;. Tissue Specificity: Expressed ubiquitously with the most abundant expression in thymus, testis, small intestine and colon. Similarity: The autoinhibitory region (AIR) inhibits the activity of the kinase domain.Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily. |
Other Names | [serine/threonine-protein kinase Chk1 isoform 1; Serine/threonine-protein kinase Chk1; serine/threonine-protein kinase Chk1; Chk1-S; checkpoint kinase-1; CHK1 checkpoint homolog; cell cycle checkpoint kinase; Checkpoint, S. pombe, homolog of, 1; checkpoint kinase 1; CHK1 checkpoint homolog; Cell cycle checkpoint kinase; Checkpoint kinase-1], [CHEK1; CHEK1; CHK1; CHK1] |
Gene, Accession # | [Chk1], Gene ID: 1111, NCBI: NP_001107593.1, UniProt: O14757 |
Catalog # | MBS001586 |
Price | $440, $715 |
Order / More Info | Rabbit Chk1 (Ab-317) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |