INAR2 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-INAR2 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | INAR2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: INAR2 antibody detects endogenous levels of total INAR2. Function: Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation (PubMed:26424569). Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1 (PubMed:8181059, PubMed:7665574, PubMed:7759950). Isoform 3 is a potent inhibitor of type I IFN receptor activity (PubMed:7759950).Subunit Structure: Heterodimer with IFNAR1 (PubMed:8181059, PubMed:7665574, PubMed:10049744, PubMed:24075985, PubMed:21854986). Isoform 1 interacts with the transcriptional factors STAT1 and STAT2 (PubMed:9121453). Interacts with JAK |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Secreted and Membrane. Tissue Specificity: Isoform 3 is detected in the urine (at protein level) (PubMed:8181059, PubMed:7759950). Expressed in blood cells. Expressed in lymphoblastoid and fibrosarcoma cell lines. |
| Other Names | [Human interferon alpha/beta receptor; IFN alpha REC; IFN R; IFN-a/betaR2; IFN-a/betaRbeta; IFN-alpha binding protein; IFN-alpha/beta receptor 2; IFN-R-2; IFNABR; IFNAR2; IFNARB; IFNR; INAR2_HUMAN; Interferon (alpha beta and omega) receptor 2; Interferon alpha binding protein; Interferon alpha/beta receptor 2; Interferon alpha/beta receptor beta chain; Type I interferon receptor 2; Type I interferon receptor] |
| Gene, Accession # | [INAR2], Gene ID: 3455, NCBI: NP_000865.2, UniProt: P48551 |
| Catalog # | MBS9604049 |
| Price | $240, $280 |
| Order / More Info | INAR2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies