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Antigenic Specificity | DKC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using DKC1 antibody. Immunofluorescence analysis of U2OS cell using DKC1 antibody. Blue: DAPI for nuclear staining. This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the NOLA1, 2 and 3 proteins. The protein encoded by this gene and the three NOLA proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. These |
Immunogen | Immunogen: Recombinant protein of human DKC1 |
Other Names | [DKC1, partial; H/ACA ribonucleoprotein complex subunit 4; H/ACA ribonucleoprotein complex subunit 4; dyskerin pseudouridine synthase 1; CBF5 homolog; Dyskerin; Nopp140-associated protein of 57 kDa; Nucleolar protein NAP57; Nucleolar protein family A member 4; snoRNP protein DKC1], [DKC1; DKC1; DKC; CBF5; DKCX; NAP57; NOLA4; XAP101; NOLA4] |
Gene, Accession # | [DKC1], Gene ID: 1736, NCBI: AKI70769.1 |
Catalog # | MBS419861 |
Price | $385 |
Order / More Info | DKC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |