Edit |   |
---|---|
Antigenic Specificity | Caspase-5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Depending on cell lines or tissues used, other cleavage products may be observed. Caspase-5 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1β and IL-18. Caspase-5 can interact with caspase-1; both are constituents of the NALP1 inflammasome, a complex that can trigger the cleavage of pro-IL-1β. |
Immunogen | Immunogen: Caspase-5 antibody was raised against a 14 amino acid synthetic peptide from the center of human Caspase-5. Buffer: Caspase-5 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [Caspase-5; ICH-3; ICEREL-III; ICE(rel)III; ICH3; Caspase-5; Protease ICH-3; CASP-5; caspase 5, apoptosis-related cysteine peptidase], [CASP5; CASP5; ICH-3; ICEREL-III; ICE(rel)III; ICH3; CASP-5] |
Gene, Accession # | [CASP5], Gene ID: 838, NCBI: P51878.2, UniProt: P51878 |
Catalog # | MBS150628 |
Price | $375 |
Order / More Info | Caspase-5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |