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Antigenic Specificity | PSMA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for Proteasome subunit alpha type-1(PSMA1) detection. Background: Proteasome subunit alpha type-1 is a protein that in humans is encoded by the PSMA1 gene. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human PSMA1 (159-204aa MSIGARSQSARTYLERHMSEFMECNLNELVKHGLRALRETLP AEQD), different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids. |
Other Names | [HC 2; HC2; PROS30; PROS-30; PROS 30; PSC 2; PSC2; PSMA 1; PSMA1; P25786; Proteasome subunit alpha type-1; proteasome subunit alpha 1], [PSMA1; PSMA1; NU; HC2; PROS30; HEL-S-275; HC2; NU; PROS30; PSC2; PROS-30] |
Gene, Accession # | [PSMA1], Gene ID: 5682, NCBI: NP_002777.1, UniProt: P25786 |
Catalog # | MBS178843 |
Price | $315 |
Order / More Info | PSMA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Groll M, Ditzel L, Lowe J, Stock D, Bochtler M, Bartunik HD, Huber R (Apr 1997). Structure of 20S proteasome from yeast at 2.4 A resolution. Nature 386 (6624): 463-71.2. Tomko RJ, Hochstrasser M (2013). Molecular architecture and assembly of the eukaryotic proteasome.Annual Review of Biochemistry 82: 415-45. |