Spectrin Alpha 1 (Erythrocyte Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Spectrin Alpha 1 (Erythrocyte Marker) |
| Clone | [SPTA1/1810] |
| Host Species | Mouse |
| Reactive Species | human. |
| Isotype | IgG2b, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | ELISA (EIA), Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous alpha and beta chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin alpha I and spectrin beta I are present in erythrocytes, whereas spectrin alpha II (also designated fodrin alpha) and spectrin beta II (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diff |
| Immunogen | Immunogen: Recombinant human SPTA fragment (around aa356-475) Cellular Localization: Cytoplasmic and Cell Surface |
| Other Names | [Alpha I spectrin; Elliptocytosis 2 (EL2); Erythrocyte alpha spectrin; Erythroid alpha-spectrin; HPP; HS3; Spectrin alpha erythrocytic 1; SPH3; SPTA1] |
| Gene, Accession # | [SPTA1], Gene ID: 6708, NCBI: NP_003117.2, UniProt: P02549 |
| Catalog # | MBS4380491 |
| Price | $190, $340, $340 |
| Order / More Info | Spectrin Alpha 1 (Erythrocyte Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Speicher, D.W. 1986. The present status of erythrocyte spectrin structure: the 106-residue repetitive structure is a basic feature of an entire class of proteins. J. Cell. Biochem. 30: 245-258. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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