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Antigenic Specificity | Synaptotagmin 6 |
Clone | [S270-47] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | APC-Cy7 conjugate |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects ~55 kDa. Does not cross-react with other synaptotagmins. Synaptotagmins constitute a family of membrane-trafficking proteins that are characterized by an N-terminal transmembrane region (TMR), a variable linker, and two C-terminal C2 domains-C2A and C2B. There are 15 members in the mammalian synaptotagmin family. There are several C2-domain containing protein families that are related to synaptotagmins, including transmembrane (Ferlins, E-Syts, and MCTPs) and soluble (RIMs, Munc13s, synaptotagmin-related proteins and B/K) proteins. The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin participa |
Immunogen | Immunogen: Fusion protein amino acids 246-333 (Cytoplasmic C2A domain) of mouse Synaptotagmin-6 |
Other Names | [Mouse Mouse Synaptotagmin-6 IgG1; Synaptotagmin-6 : APC/Cy7; SYT-6; SYT6; Synaptotagmin 6; Synaptotagmin VI; SytVI; Syt VI; Synaptotagmin6; SynaptotagminVI] |
Gene, Accession # | [SYT6], Gene ID: 54524, NCBI: NP_061270.2, UniProt: Q9R0N8 |
Catalog # | MBS8003244 |
Price | $510 |
Order / More Info | Synaptotagmin 6 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Schengrund C.L., et al. (2002) J Biol Chem. 277: 32815. 2. Reichardt L.F., et al. (1981) J Cell Biol. 91:257. |