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Antigenic Specificity | CD8A (C-term), 150-180 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CD8A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-180 amino acids from the C-terminal region of human CD8A. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a co-receptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional co-receptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. |
Immunogen | n/a |
Other Names | [T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; CD8a; CD8A; MAL] |
Gene, Accession # | [CD8A], Gene ID: 925, NCBI: NP_001139345.1, UniProt: P01732 |
Catalog # | MBS9203871 |
Price | $165, $370 |
Order / More Info | CD8A (C-term), 150-180 Antibody from MYBIOSOURCE INC. |
Product Specific References | Mancebo,E., Mol. Immunol. 45 (2), 479-484 (2008) Zhou,H., Transplant. Proc. 39 (10), 3065-3067 (2007) Borchers,M.T., Exp. Mol. Pathol. 83 (3), 301-310 (2007) |