Edit |   |
---|---|
Antigenic Specificity | NELF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NELF Antibody: NELF (nasal embryonic luteinizing hormone-releasing hormone factor) is a 530 amino acid transcription factor involved in the migration of LHRH neurons, outgrowth of olfactory axons and suppression of transcription elongation. NELF is found in the peripheral and central nervous system during embryonic development, and is highly expressed in adult testis, kidney and brain. Known to couple NMDA receptor signaling to the nucleus, NELF knockdown impaired GnRH neuronal migration of NLT cells in vitro and the gene encoding NELF has been linked to the development of Idiopathic hypogonadotropic hypogonadism (IHH), a disorder resulting in impaired pubertal maturation and reproductive function. |
Immunogen | Immunogen: Rabbit polyclonal NELF antibody was raised against a 17 amino acid peptide near the center of human NELF. Buffer: NELF Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [NELF; HH9; NELF; NMDA receptor synaptonuclear signaling and neuronal migration factor; Nasal embryonic luteinizing hormone-releasing hormone factor; Nasal embryonic LHRH factor; nasal embryonic LHRH factor], [NSMF; NSMF; HH9; NELF; NELF; Nasal embryonic LHRH factor] |
Gene, Accession # | [NELF], Gene ID: 26012, NCBI: NP_056352, UniProt: Q6X4W1 |
Catalog # | MBS153558 |
Price | $375 |
Order / More Info | NELF Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |