KITLG (C-term) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | KITLG (C-term) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This KITLG antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 201-234 amino acids from the C-terminal region of human KITLG. Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. |
| Immunogen | n/a |
| Other Names | [Kit ligand; Mast cell growth factor; MGF; Stem cell factor; SCF; c-Kit ligand; Soluble KIT ligand; sKITLG; KITLG; MGF; SCF] |
| Gene, Accession # | [KITLG], Gene ID: 4254, NCBI: NP_000890.1, UniProt: P21583 |
| Catalog # | MBS9210711 |
| Price | $165, $370 |
| Order / More Info | KITLG (C-term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Martin F.H.,et al.Cell 63:203-211(1990). Anderson D.M.,et al.Cell Growth Differ. 2:373-378(1991). Blair H.C.,et al.Biochem. Biophys. Res. Commun. 255:778-784(1999). Han C.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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