Elafin/Skalp Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Elafin/Skalp |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human. |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit IgG polyclonal antibody for Elafin (PI3) detection. Background: Elafin, also known as peptidase inhibitor 3 or skin-derived antileukoprotease (SKALP), is a protein that in humans is encoded by the PI3 gene. This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. And this gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines. |
| Immunogen | Immunogen: E Coli-derived human Elafin/Skalp recombinant protein (Position: A61-Q117). |
| Other Names | [Cementoin; Elafin; ES 1; ESI; PI3; PI-3; PI 3; SKALP; Trappin 2; WAP3; WFDC14; P19957; Elafin; peptidase inhibitor 3], [PI3; PI3; ESI; WAP3; SKALP; WFDC14; cementoin; WAP3; WFDC14; ESI; PI-3; SKALP] |
| Gene, Accession # | [PI3], Gene ID: 5266, NCBI: NP_002629.1, UniProt: P19957 |
| Catalog # | MBS178457 |
| Price | $315 |
| Order / More Info | Elafin/Skalp Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Entrez Gene: PI3 peptidase inhibitor 3, skin-derived (SKALP).2. Clauss A, Lilja H, Lundwall A (Nov 2002). A locus on human chromosome 20 contains several genes expressing protease inhibitor domains with homology to whey acidic protein. Biochem J 368 (Pt 1): 233-42.3. Molhuizen HO, Zeeuwen PL, Olde Weghuis D, Geurts van Kessel A, Schalkwijk J (Feb 1994). Assignment of the human gene encoding the epidermal serine proteinase inhibitor SKALP (PI3) to chromosome region 20q12-->q13. Cytogenet Cell Genet 66 (2): 129-31. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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