HAX-1, Human Antibody from NKMAX Co. Ltd.

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Antigenic SpecificityHAX-1, Human
CloneAT3C5
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b kappa
FormatProtein G purified
Size50ul, 100ul
Concentration1mg/ml (determined by BCA assay)
ApplicationsELISA,WB,ICC/IF
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DescriptionHAX1 is known to associate with hematopoietic cell-specific Lyn substrate 1 (HS1), one of the substrates of receptor-coupled tyrosine kinases activated during clonal expansion and deletion in lymphoid cells. It also interacts with the product of the polycystic kidney disease 2 (PKD2) gene and with the F-actin-binding protein, cortactin. HAX1 is also reported to bind to hairpin structures in vimentin and DNA polymerase beta mRNAs, so may play a role in mRNA stability and transport. It may also function in promoting cell survival. Defects in HAX1 are the cause of autosomal recessive severe congenital neutropenia 3 (SCN3) also called Kostmann disease.
ImmunogenRecombinant human HAX1 (1-279aa) purified from E. coli
Other NamesHCLS1 associated protein X-1, HS1BP1, HCLSBP1, HCLS1 (and PKD2) associated protein
Gene, Accession #NCBI: NP_006109, UniProt: O00165
Catalog #ATGA0156
Price$170, $290
Order / More InfoHAX-1, Human Antibody from NKMAX Co. Ltd.
Product Specific Referencesn/a
NKMAX Co. Ltd.
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124

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