Edit |   |
---|---|
Antigenic Specificity | EPM2A, Human |
Clone | k2A3 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | Protein G purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA,WB,ICC/IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Epilepsy, progressive myoclonus type 2A (EPM2A), also known as laforin, is a dual-specificity phosphatase that associates with polyribosomes. The protein may be involved in the control of glycogen metabolism, particularly in monitoring for and preventing the formation of poorly branched glycogen molecules. Defects in EPM2A are a cause of progressive myoclonic epilepsy type 2 (EPM2), also known as Lafora disease. EPM2 is an autosomal recessive and severe form of adolescent-onset progressive epilepsy. |
Immunogen | Recombinant human EPM2A (243-331aa) purified from E. coli |
Other Names | Laforin isoform a,epilepsy, progressive myoclonus type 2A Lafora disease (laforin), epilepsy progressive myoclonus type 2 Lafora disease (laforin), LDE, LD |
Gene, Accession # | NCBI: NP_005661, UniProt: O95278 |
Catalog # | AEP0911 |
Price | $170, $290 |
Order / More Info | EPM2A, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |