Ras, Human Antibody from NKMAX Co. Ltd.

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Antigenic SpecificityRas, Human
CloneAT2F8
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b kappa
FormatProtein A purified
Size50ul, 100ul
Concentration1mg/ml (determined by BCA assay)
ApplicationsELISA,WB,ICC/IF
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DescriptionAll RAS protein family members belong to a class of protein called small GTPase, and are involved cellular signal transduction. RAS is 'switched on' by incoming signals, it subsequently switches on other proteins, which ultimately turn on genes involved in cell growth, differentiation and survival. Mutations in RAS genes can lead to the production of permanently activated RAS proteins. This can cause unintended and overactive signaling inside the cell, even in the absence of incoming signals. Because these signals result in cell growth and division, overactive RAS signaling can ultimately lead to cancer. The 3 Ras genes in humans (HRas, KRas, NRas) are the most common oncogenes in human cancer; mutations that permanently activate RAS are found in 20% to 25% of all human tumors and up to 90% in certain types of cancer. RAS inhibitors are being studied as a treatment for cancer, and other diseases with RAS overexpression.
ImmunogenRecombinant human KRAS (1-186aa) purified from E. coli
Other NamesGTPase Kras, C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, NS3, RASK2, GTPase Kras,K-RAS2A, K RAS2B, K RAS4A, K RAS4B, KI RAS, KRAS 1, NS 3
Gene, Accession #NCBI: NP_203524, UniProt: P01116
Catalog #ATGA0350
Price$170, $290
Order / More InfoRas, Human Antibody from NKMAX Co. Ltd.
Product Specific Referencesn/a
NKMAX Co. Ltd.
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124

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