GRP78/HSPA5, Human Antibody from NKMAX Co. Ltd.

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Antigenic SpecificityGRP78/HSPA5, Human
CloneAT3D2
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1 kappa
FormatProtein A purified
Size50ul, 100ul
Concentration1mg/ml (determined by BCA assay)
ApplicationsELISA, WB, ICC/IF
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DescriptionBinding immunoglobulin protein (BIP) also known as 78kDa glucose-regulated protein (GRP-78) or heat shock 70kDa protein 5 (HSPA5) is a HSP70 molecular chaperone located in the lumen of the endoplasmic reticulum (ER) that binds newly synthesized proteins as they are translocated into the ER, and maintains them in a state competent for subsequent folding and oligomerization. BIP is also an essential component of the translocation machinery, as well as playing a role in retrograde transport across the ER membrane of aberrant proteins destined for degradation by the proteasome. BIP is an abundant protein under all growth conditions, but its synthesis is markedly induced under conditions that lead to the accumulation of unfolded polypeptides in the ER.
ImmunogenRecombinant human BIP (20-650aa) purified from Baculo virus
Other NamesHeat shock protein family A member 5, Heat shock 70kD protein 5, HSP70 family protein 5, Glucose-regulated protein 78kD, Binding-immunoglobulin protein, BiP, Endoplasmic reticulum chaperone BiP, Glucose-regulated protein 78kDa, Immunoglobulin heavy chain-binding protein
Gene, Accession #NCBI: NP_005338, UniProt: P11021
Catalog #ATGA0320
Price$170, $290
Order / More InfoGRP78/HSPA5, Human Antibody from NKMAX Co. Ltd.
Product Specific Referencesn/a
NKMAX Co. Ltd.
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124

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