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Antigenic Specificity | TFAM |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | serum, no preservative |
Size | 100 µL |
Concentration | n/a |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TFAM Antibody is a prepared sterile filtered neat serum. Mitochondrial Transcription Factor A (TFAM) is a key activator of mitochondrial (mt) DNA transcription as well as a participant in mitochondrial genome replication. mtDNA is highly susceptible to oxidative stress leading to mitochondrial dysfunction. Overexpression of TFAM has been implicated in the amelioration of age dependent impairment of brain functions through the prevention of oxidative stress and mitochondrial dysfunction in microglia. More recently, TFAM overexpression has been shown to potentially reduce oxidative stress in motor neurons and delay onset of amyotrophic lateral sclerosis (ALS) in ALS model mice. TFAM Antibody is ideal for researchers interested in neuroscience research. |
Immunogen | Anti-TFAM Antibody was produced in rabbits by repeated immunizations with a native recombinant mouse TFAM protein with c-terminal 6-his tag. |
Other Names | Transcription factor A mitochondrial, mtTFA, Testis-specific high mobility group protein, TS-HMG |
Gene, Accession # | Tfam, Gene ID: 21780, NCBI: NP_033386.1, UniProt: P40630 |
Catalog # | 100-401-X30 |
Price | $475 |
Order / More Info | TFAM Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |