LIN28 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | LIN28 |
| Clone | 1G9H9 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b |
| Format | peptide affinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Lin28 Monoclonal Antibody is affinity chromatography purified via peptide column. At least two isoforms of Lin28 are known to exist; this antibody will detect both. Lin28 antibody will not cross-react with Lin28 Homolog B. Lin28 is a transcription factor that was first identified through its key role in the pathway of developmental timing in C. elegans. The role of Lin28 in development suggested that it might be useful in the creation of stem cells that might be beneficial in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing Lin28 in addition to the transcription factors POU5F1, Sox2, and NANOG in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing Lin28, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine. |
| Immunogen | Anti-Lin28 antibody was produced in mice by repeated immunizations with a 15 amino acid peptide near the C-terminus of human Lin28. |
| Other Names | LIN28 Antibody, CSDD1, LIN-28, ZCCHC1, lin-28A |
| Gene, Accession # | LIN28A, Gene ID: 79727, NCBI: EAX07814, UniProt: Q9H9Z2 |
| Catalog # | 200-301-CL0 |
| Price | $485 |
| Order / More Info | LIN28 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.