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Antigenic Specificity | SIRT7 |
Clone | polyclonal |
Host Species | Chicken |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-SIRT7 Antibody is an IgY fraction that has been affinity purified by immunoaffinity purification. Cross reactivity with SIRT7 from other sources has not been determined. The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT7 is a nucleolar protein that positively regulates RNA polymerase I transcription and has been postulated to enable cells to sustain critical functions by inhibiting cell growth under severe stress conditions. |
Immunogen | Anti-SIRT7 antibody was prepared from chicken egg fractions produced by repeated immunizations with a 19 amino acid synthetic peptide near the N-terminus of human SIRT7. |
Other Names | SIRT7 Antibody, SIR2L7, SIR2L7, NAD-dependent protein deacetylase sirtuin-7, Regulatory protein SIR2 homolog 7 |
Gene, Accession # | SIRT7, Gene ID: 51547, NCBI: NP_057622, UniProt: Q9NRC8 |
Catalog # | 200-901-EM2 |
Price | $475 |
Order / More Info | SIRT7 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |