ARTEMIS Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityARTEMIS
Clonepolyclonal
Host SpeciesGoat
Reactive Specieshuman
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1.2 mg/mL
ApplicationsELISA, Immunohistochemistry, Western Blot
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DescriptionThis is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase. This antibody detects a band of the appropriate size in a number of different cell lines. However, it does not detect a band in cell lines that do not express artemis, such as the cell line CJ (see figure) and in an hTERT line (not shown). Artemis has a role in T and B lymphocyte immunodeficiency and in predisposition to lymphoma through the NHEJ pathway of DNA repair. DNA-PKcs regulates Artemis by both phosphorylation and complex formation to permit enzymatic activities that are critical for the hairpin-opening step of V(D)J recombination and for the 5' and 3' overhang processing in non-homologous DNA end joining.
ImmunogenThis affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding an internal region of Human ARTEMIS (DCLRE1C DNA cross-link repair 1C).
Other Namesgoat anti-Artemis Antibody, A-SCID antibody, A SCID protein antibody, protein Artemis antibody, DCLRE1C antibody, DCLRE1C, DNA cross link repair 1C antibody, ASCID, SCIDA, SNM1C
Gene, Accession #DCLRE1C, Gene ID: 64421, NCBI: 76496495, UniProt: Q96SD1
Catalog #600-101-293
Price$475
Order / More InfoARTEMIS Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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