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Antigenic Specificity | Alpha-Tubulin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Alpha-tubulin antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Alpha-tubulin antibody is human, mouse and rat reactive. Alpha-tubulin belongs to the tubulin superfamily, which is composed of six distinct families. Along with beta-tubulins, alpha-tubulins are the major components of microtubules. These microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Alpha- and beta-tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter. Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha-tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase. Another post-translational modification of detyrosinated alpha-tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle. Like GAPDH and beta-Actin, this antibody makes an excellent loading control in immunoblots. |
Immunogen | Anti-Alpha-tubulin antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the N-terminus of human alpha-tubulin |
Other Names | Alpha-tubulin Antibody, TUBA2, bA408E5.3, TUBA2, TUBA3D, Alpha-tubulin 2 |
Gene, Accession # | TUBA3C, Gene ID: 7278, NCBI: NP_005992, UniProt: P0DPH7 |
Catalog # | 600-401-Y07 |
Price | $475 |
Order / More Info | Alpha-Tubulin Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |