Edit |   |
---|---|
Antigenic Specificity | ATG14 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ATG14 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least three isoforms of ATG14 are known to exist; this antibody will detect all three isoforms. Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein ATG1. ATG14 is a subunit of a class III phosphatidylinositol (PtdIns) 3-kinase complex that targets the complex to the endoplasmic reticulum, the site of autophagosome formation. |
Immunogen | Anti-ATG14 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid synthetic peptide near the internal region of human ATG14. |
Other Names | ATG14 Antibody, ATG14L, BARKOR, KIAA0831, Beclin 1-associated autophagy-related key regulator, Autophagy-related protein 14-like protein, Barkor |
Gene, Accession # | ATG14, Gene ID: 22863, NCBI: NP_055739, UniProt: Q6ZNE5 |
Catalog # | 600-401-Y77 |
Price | $475 |
Order / More Info | ATG14 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |