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Antigenic Specificity | TFEB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TFEB antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. TFEB antibody is human specific. At least three isoforms of TFEB are known to exist. The Transcription factor EB (TFEB) is a member in the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors (1,2). Recent studies have shown that lysosomal biogenesis is regulated by TFEB (3), which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1 (4). Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes (5). |
Immunogen | Anti- TFEB antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid peptide near the C-terminus of human TFEB. |
Other Names | TFEB Antibody, TCFEB, BHLHE35, ALPHATFEB, Transcription factor EB, Class E basic helix-loop-helix protein 35, bHLHe35 |
Gene, Accession # | TFEB, Gene ID: 7942, NCBI: NP_001161299.2, UniProt: P19484 |
Catalog # | 600-401-FD1 |
Price | $475 |
Order / More Info | TFEB Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |