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Antigenic Specificity | KANK3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-KANK3 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Two alternatively spliced transcript variants encoding different isoforms have been identified. Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. Like other members of the KANK family, KANK3 (KN motif and ankyrin repeat domain-containing protein 3), is thought to play a role in the formation of actin stress fibers. In zebrafish, the homolog of KANK3 interacts with the adaptor protein Numb, a protein implicated in multiple basic cellular processes, and is essential for epidermal integrity and neurulation, suggesting that KANK3 may play a similar role in higher organisms. |
Immunogen | Anti-KANK3 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the N-terminus of human KANK3. |
Other Names | KANK3 Antibody, ANKRD47, ANKRD47, KN motif and ankyrin repeat domain-containing protein 3, Ankyrin repeat domain-containing protein 47 |
Gene, Accession # | KANK3, Gene ID: 256949, NCBI: NP_940873, UniProt: Q6NY19 |
Catalog # | 600-401-CD4 |
Price | $475 |
Order / More Info | KANK3 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |