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Antigenic Specificity | RASSF10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-RASSF10 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. RASSF10 antibody will not cross-react with other RAS association domain-containing family members. RASSF10 is a member of the N-terminal Ras association domain-containing family of proteins, a family of tumor suppressor genes that are frequently epigenetically inactivated in cancer. These proteins consist of RASSF7-10 and are structurally distinct from RASSF1-6, containing the N-terminal Ras association domain but lacking the Sav/RASSF/Hippo protein interaction domains. While little is known of the function of RASSF10, it is inactivated in both childhood leukemia and gliomas. In secondary glioblastomas, RASSF10 methylation can be used as an independent prognostic associated with worst progression-free survival and overall survival. |
Immunogen | Anti-RASSF10 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the N-terminus of human RASSF10. |
Other Names | RASSF10 Antibody, Ras association domain-containing protein 10 |
Gene, Accession # | RASSF10, Gene ID: 644943, NCBI: NP_001073990, UniProt: A6NK89 |
Catalog # | 600-401-DW7 |
Price | $475 |
Order / More Info | RASSF10 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |