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Antigenic Specificity | Mitofusin 2 |
Clone | S153-5 |
Host Species | Mouse |
Reactive Species | mouse, rat |
Isotype | IgG2a |
Format | peroxidase (HRP) conjugate |
Size | 100 µg |
Concentration | 1mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Mitofusin 2 Antibody was purified from concentrated tissue culture supernate by Protein G chromatography. BLAST analysis suggests that it is 97% identical to rat, 92% identical to human and ~55% identical to Mitofusin 1. Mitofusin-2 (Mfn2) is a membrane protein of the mitochondria and is important in mitochondrial fusion in mammalian cells. Mfn2 activity has also been implicated in mitochondrial metabolism and the loss of Mfn2 may be the reason for certain metabolic modifications that are seen in individuals with obesity. Mfn2 has been associated with maintaining the membrane potential of the mitochondria. Mfn2 has been shown to hinder mitochondrial antiviral signaling by inhibiting production of type 1 interferons. Mfn2 is a p53-inducible target and involved in cell proliferation, apoptosis promotion and tumor suppression. Anti-Mitofusin-2 is ideal for research in Metabolic Processes and Hemostasis. |
Immunogen | Anti-Mitofusin 2 Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 370-600 of mouse Mitofusin 2. |
Other Names | CMT2A, CMT2A2, CPRP 1, CPRP1, Fzo, HSG, hyperplasia suppressor gene, Hypertension related protein 1, KIAA0214, MARF, MFN 2, Mfn2, Mitochondrial assembly regulatory factor, Mitofusin-2, Mitofusin2, Transmembrane GTPase MFN2 |
Gene, Accession # | Mfn2, Gene ID: 170731, UniProt: Q80U63 |
Catalog # | 200-303-W71 |
Price | $495 |
Order / More Info | Mitofusin 2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |