Sipa1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificitySipa1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1.25 mg/mL
ApplicationsELISA, Immunohistochemistry, Western Blot
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DescriptionThis product was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is specific for mouse Sipa1 protein. A BLAST analysis was used to suggest cross-reactivity with Sipa1 from mouse, human and rat based on a 100% homology with the immunizing sequence. Cross-reactivity with Sipa1 from other sources has not been determined. This antibody is designed, produced, and validated as part of a collaboration between Rockland and the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. Sipa1 (signal-induced proliferation associated gene 1) is a mitogen-induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. Sipa1 is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.
ImmunogenThis affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the amino terminus of mouse Sipa1.
Other Namesrabbit anti-Sipa1 antibody, Sipa-1, Sipa 1, GTPase activating protein Spa 1 antibody, p130 SPA-1 antibody, Signal induced proliferation associated 1 antibody, SPA1
Gene, Accession #Sipa1, Gene ID: 20469, NCBI: AAH54824.1, UniProt: P46062
Catalog #600-401-A36
Price$475
Order / More InfoSipa1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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