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Antigenic Specificity | LPIN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-LPIN1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. LPIN1 antibody is human and mouse reactive. At least four isoforms of LPIN1 are known to exist. LPIN1, also known as PAP1, is a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol (reviewed in 1). LPIN1 is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism (1,2). Mutations in LPIN1 are associated with metabolic diseases such as type 2 diabetes and recurrent acute myoglobinuria (3,4) and it is also a candidate for several human lipodystrophy syndromes (5). |
Immunogen | Anti-LPIN1 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the C-terminus of human LPIN1. |
Other Names | LPIN1 Antibody, PAP1, KIAA0188, Phosphatidate phosphatase LPIN1, Lipin-1 |
Gene, Accession # | LPIN1, Gene ID: 23175, NCBI: NP_001248357, UniProt: Q14693 |
Catalog # | 600-401-CL9 |
Price | $475 |
Order / More Info | LPIN1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |