Edit |   |
---|---|
Antigenic Specificity | LMX1A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-LMX1A Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms are known to exist. This antibody is predicted to not cross-react with LMX1B. The LIM homeobox transcription factor 1 (LMX1A) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1A binds an A/T-rich sequence and functions in the nucleus as a transcriptional activator to the insulin gene promoter. In the developing embryo, LMX1A is expressed along the neuraxis and leads to the development of the roof plate of the vertebrae. While LMX1A is crucial for the differentiation of dopamine neurons, the related LMX1B appears to be important for both the development and the survival of these cells. It has been suggested that LMX1A might be a useful biomarker or risk factor in tumor aggressiveness. |
Immunogen | Anti- LMX1A antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid peptide near the C-terminus of human LMX1A. |
Other Names | LMX1A Antibody, LMX1, LMX1.1, LIM homeobox transcription factor 1-alpha |
Gene, Accession # | LMX1A, Gene ID: 4009, NCBI: NP_796372, UniProt: Q8TE12 |
Catalog # | 600-401-CL6 |
Price | $475 |
Order / More Info | LMX1A Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |