LMX1A Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityLMX1A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, Immunohistochemistry, IF Microscopy, Western Blot
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DescriptionAnti-LMX1A Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms are known to exist. This antibody is predicted to not cross-react with LMX1B. The LIM homeobox transcription factor 1 (LMX1A) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1A binds an A/T-rich sequence and functions in the nucleus as a transcriptional activator to the insulin gene promoter. In the developing embryo, LMX1A is expressed along the neuraxis and leads to the development of the roof plate of the vertebrae. While LMX1A is crucial for the differentiation of dopamine neurons, the related LMX1B appears to be important for both the development and the survival of these cells. It has been suggested that LMX1A might be a useful biomarker or risk factor in tumor aggressiveness.
ImmunogenAnti- LMX1A antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid peptide near the C-terminus of human LMX1A.
Other NamesLMX1A Antibody, LMX1, LMX1.1, LIM homeobox transcription factor 1-alpha
Gene, Accession #LMX1A, Gene ID: 4009, NCBI: NP_796372, UniProt: Q8TE12
Catalog #600-401-CL6
Price$475
Order / More InfoLMX1A Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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