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Antigenic Specificity | Jarid1b |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | serum |
Size | 100 µL |
Concentration | neat |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Jarid1b Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. Cross reactivity with Jarid1b from other species not tested. JARID1B is a histone demethylase which specifically demethylates mono-, di, and trimethylated lysine 4 of histone H3. It acts as a transcriptional repressor for the tumor suppressor genes BRCA1 and HOXA5 and has been associated with breast cancer development. In contrast, in melanoma JARID1B itself may function as a tumor suppressor. Anti-Jarid1b Antibody is ideal for research in Epigenetics, Chromatin Remodeling and Cancer. |
Immunogen | Anti-Jarid1b Antibody was produced in rabbits by repeated immunizations with a synthetic peptide containing an amino acid sequence from the internal part of mouse Jarid1b. |
Other Names | Lysine-specific demethylase 5B, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B, PLU-1 |
Gene, Accession # | Kdm5b, Gene ID: 10765, NCBI: NP_006609.3, UniProt: Q80Y84 |
Catalog # | 100-401-V92 |
Price | $445 |
Order / More Info | Jarid1b Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |