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Antigenic Specificity | WWC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/ml |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-WWC1 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. WWC1 antibody is human, mouse and rat reactive. At least three isoforms of WWC1 are known to exist; this antibody will detect all three isoforms. The WW and C2 domain containing 1 (WWC1) protein, also known as KIBRA, possesses two WW domains and an internal C2-like domain (1). WWC1 was originally identified as a memory performance-associated protein in humans (2) and has recently been shown to be a novel regulator of the Hippo pathway (3). WWC1 is phosphorylated by the mitotic kinases Aurora-A and -B (4), and in turn activates the Aurora kinases and is required for precise chromosome alignment during mitosis (5). |
Immunogen | Anti-WWC1 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the N-terminus of human WWC1. |
Other Names | WW and C2 domain containing 1, HBEBP3, HBEBP36, KIBRA, MEMRYQTL, HBeAg-binding protein 3, Kidney and brain protein, KIBRA, WW domain-containing protein 1 |
Gene, Accession # | WWC1, Gene ID: 23286, NCBI: NP_001155133.1, UniProt: Q8IX03 |
Catalog # | 600-401-FZ5 |
Price | $475 |
Order / More Info | WWC1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |