WWC1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityWWC1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1.0 mg/ml
ApplicationsELISA, Immunohistochemistry, IF Microscopy, Western Blot
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DescriptionAnti-WWC1 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. WWC1 antibody is human, mouse and rat reactive. At least three isoforms of WWC1 are known to exist; this antibody will detect all three isoforms. The WW and C2 domain containing 1 (WWC1) protein, also known as KIBRA, possesses two WW domains and an internal C2-like domain (1). WWC1 was originally identified as a memory performance-associated protein in humans (2) and has recently been shown to be a novel regulator of the Hippo pathway (3). WWC1 is phosphorylated by the mitotic kinases Aurora-A and -B (4), and in turn activates the Aurora kinases and is required for precise chromosome alignment during mitosis (5).
ImmunogenAnti-WWC1 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the N-terminus of human WWC1.
Other NamesWW and C2 domain containing 1, HBEBP3, HBEBP36, KIBRA, MEMRYQTL, HBeAg-binding protein 3, Kidney and brain protein, KIBRA, WW domain-containing protein 1
Gene, Accession #WWC1, Gene ID: 23286, NCBI: NP_001155133.1, UniProt: Q8IX03
Catalog #600-401-FZ5
Price$475
Order / More InfoWWC1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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