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Antigenic Specificity | Histone H3 K18me2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, C. elegans |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 50 µg |
Concentration | 0.79 mg/ml |
Applications | Chip, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Histone H3 [Dimethyl Lys18] was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody reacts with human Histone H3.2. A BLAST analysis was used to suggest cross-reactivity with Human, mouse, and C. elegans. Predicted to react with many species including rat, chicken, Xenopus, Drosophila, and plant based on 100% sequence homology. Cross-reactivity with Histone H3 from other sources has not been determined. The di-methylated K18 on histone H3 is a seemingly transient post-translational modification. H3K18 is better known to be acetylated, and occasionally mono-methylated. Suv39h1, a well-studied histone methyltransferase seems to be responsible for the transition of acetylation and methylation at this H3 modification site. The di-methylated K18 on H3 seems to be associated with embryological development and possibly implantation. Anti-Histone H3 are ideal for researchers interested in Chromatin Modifiers, Chromatin Research, Histones and Modified Histones, and Epigenetics research. |
Immunogen | Histone H3 [Dimethyl Lys18] affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic dimethylated peptide surrounding Lysine 18 of human Histone H3.2. |
Other Names | rabbit anti-Histone H3 dimethyl Lys18 antibody, H3.3AH3F3H3F3B, H3.3B, H3 histone, family 3A, histone H3.3, MGC87783, MGC87782, H3K18me2 |
Gene, Accession # | HIST2H3C, Gene ID: 126961, NCBI: NP_001005464, UniProt: Q71DI3 |
Catalog # | 600-401-I79 |
Price | $495 |
Order / More Info | Histone H3 K18me2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |