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Antigenic Specificity | Wnt10a |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Wnt10a Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Despite the high homology of Wnt10a to Wnt10b, this Wnt10a antibody will not cross-react with Wnt10b. Wnt10a is a member of the Wnt family, a gene family that encodes secreted signaling proteins that play crucial roles in normal development such as regulation of cell fate and patterning during embryogenesis as well as neoplastic transformation. Elevated levels of Wnt10a have been detected in several human tumors and cancer cell lines including colorectal cancer and chronic lymphocytic leukemia and it has been suggested that uncontrolled Wnt signaling may contribute to the defect in apoptosis that characterizes these malignancies. Recently, a mutation in Wnt10a was found to be associated with odonto-onycho-dermal dysplasia, an autosomal recessive ectodermal dysplasia. |
Immunogen | Anti-Wnt10a antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide from near the C-terminus of human Wnt10a. |
Other Names | Wnt10a Antibody, OODD, SSPS, STHAG4, Protein Wnt-10a |
Gene, Accession # | WNT10A, Gene ID: 80326, NCBI: NP_079492.2, UniProt: Q9GZT5 |
Catalog # | 600-401-FZ3 |
Price | $475 |
Order / More Info | Wnt10a Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |