GRIK4 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | GRIK4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Grik4 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Grik4 from other sources has not been determined. Grik4 codes for the KA1 subunit of kainate-type ionotropic glutamate receptors which are critical regulators of network activity that act by modifying neuronal excitability, directly and indirectly, through GABAergic interneurons. Five subunits can assemble to form kainate receptors (KARs): GluR5 (coded by Grik1), GluR6 (coded by Grik2), and GluR7 (coded by Grik3) are the low-affinity subunits, and KA1 and KA2 are the high-affinity subunits. In the adult brain, KARs are located pre- and postsynaptically on pyramidal cells and on interneurons. Kainate receptors on GABA-containing interneurons enhance GABA release and thereby downregulate glutamatergic signaling. KARs have been implicated in numerous psychiatric disorders. Case control studies show significant association of Grik4 with both schizophrenia and bipolar disorder. |
| Immunogen | Anti-Grik4 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide near the N-terminus of the human Grik4. |
| Other Names | Grik4 Antibody, KA1, EAA1, GRIK, GluK4, Glutamate receptor ionotropic, kainate 4, Excitatory amino acid receptor 1 |
| Gene, Accession # | GRIK4, Gene ID: 2900, NCBI: NP_001269399.1, UniProt: Q16099 |
| Catalog # | 600-401-BN9 |
| Price | $475 |
| Order / More Info | GRIK4 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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