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Antigenic Specificity | EphA10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-EphA10 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with EphA10 from other sources has not been determined. Eph receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility of neuronal and endothelial cells in central nervous system function and in development. Eph receptors can be divided into two subgroups: EphA and EphB. In mammals, the EphA class consists of eight members (EphA 1-7 and 10) that in general bind to ephrin-A members linked to the cell membrane through a glycosylphosphatidylinositol linkage. The EphB class consists of six members (EphB 1-6) that in general bind ephrin-B members that transverse the cell membrane. The Ephrin / EPH signaling pathway networks with the WNT signaling pathway during embryogenesis, tissue regeneration, and carcinogenesis. Recent studies show that Eph/EFN might be relevant in normal B-cell biology and could represent new potential prognostic markers and therapeutic targets for CLL. |
Immunogen | Anti-EphA10 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide of near the N-terminus of human EphA10. |
Other Names | EphA10 Antibody, Ephrin type-A receptor 10 |
Gene, Accession # | EPHA10, Gene ID: 284656, NCBI: NP_001092909, UniProt: Q5JZY3 |
Catalog # | 600-401-BB3 |
Price | $475 |
Order / More Info | EphA10 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |